Results for group comparisons between patients with MDD healthy controls*
| Brain region | Cluster size, k | MNI (at peak), x, y, z | Side | t | pFWE |
|---|---|---|---|---|---|
| Insula/superior temporal gyrus/middle temporal gyrus/rolandic operculum | 3479 | 60, −24, −6 | Right | 4.86 | < 0.001 |
| Superior frontal gyrus/medial frontal gyrus, orbital part/middle frontal gyrus/superior frontal gyrus, medial part | 1764 | −8, 68, 8 | Left | 4.78 | 0.002 |
| Middle frontal gyrus/inferior frontal gyrus, orbital part/middle frontal gyrus, orbital part | 1109 | 38, 52, 27 | Right | 4.69 | 0.014 |
FWE = family-wise error; MDD = major depressive disorder; MNI = Montreal Neurological Institute.
↵* Including age, sex and total intracranial volume as nuisance regressors.