Results of the gene-based association test of LRP1 across several psychiatric disorders using summary statistics of the PGC2 data sets
| Condition | Cases/controls | SNPs tested | p value | Top SNP | Top SNP p value |
|---|---|---|---|---|---|
| Attention-deficit/hyperactivity disorder | 19099/34194 | 112 | 0.10 | rs34577247 | 0.002 |
| Anorexia nervosa | 3495/10982 | 149 | 0.41 | rs2228187 | 0.008 |
| Autism-spectrum disorder | 6197/7377 | 80 | 0.99 | rs11172113 | 0.25 |
| Bipolar disorder | 20352/31358 | 219 | 0.06 | rs10467125 | 0.001 |
| Major depressive disorder | 59851/113154 | 254 | 0.49 | rs113379328 | 0.006 |
| Obsessive–compulsive disorder | 2688/7037 | 137 | 0.36 | rs7398375 | 0.003 |
| Schizophrenia | 33640/43456 | 227 | 6.6 × E−07 | rs12814239 | 2.91 × E−09 |
| Meta-analysis | 2.3 × E−03 |
PCG2 = Psychiatric Genomics Consortium 2; SNP = single nucleotide polymorphism.