Participant demographic and clinical characteristics at baseline
| Pt. no. | Sex/age, yr | Primary OCD symptoms | Psychiatric comorbidity | Illness duration/ treatment duration, yr | Current medications | Previously failed medications |
|---|---|---|---|---|---|---|
| 1 | M/24 | Contamination fear, washing, counting | Major depressive disorder | 11/5 | Escitalopram 40 mg, valproic acid 250 mg, alprazolam 0.25 mg | Fluoxetine 60 mg, paroxetine 60 mg, clomipramine 100 mg, risperidone 3 mg |
| 2 | M/29 | Contamination fear, washing | Obsessive-compulsive personality traits | 17/11 | Fluoxetine 80 mg, escitalopram 30 mg, buspirone 20 mg | Fluoxetine 80 mg, sertraline 200 mg, quetiapine 300 mg, aripiprazole 15 mg, escitalopram 40 mg, clomipramine 150 mg |
| 3 | M/22 | Aggressive obsession, washing, counting | Major depressive disorder | 13/8 | Sertraline 200 mg, clomipramine 100 mg, aripiprazole 15 mg, risperidone 10 mg, olanzapine 5 mg | Escitalopram 20 mg, sertraline 300 mg, fluoxetine 80 mg, venlafaxine XR 150 mg, quetiapine 800 mg, risperidone 4 mg, aripiprazole 15 mg, palliperidone 9 mg |
| 4 | F/44 | Pathologic doubt, checking | Major depressive disorder | 24/19 | Fluoxetine 80 mg, olanzapine 10 mg | Clomipramine 125 mg, paroxetine 40 mg, fluoxetine 80 mg, escitalopram 30 mg, aripiprazole 15 mg, olanzapine 20 mg |
| 5 | F/37 | Contamination fear, washing | Minor depression | 10/8 | Fluvoxamine 150 mg, venlafaxine XR 75 mg, chlorpromazine 50 mg, clonazepam 0.5 mg | Fluoxetine 80 mg, clomipramine 100 mg, fluvoxamine 300 mg, venlafaxine XR 112.5 mg, aripiprazole 10 mg |
| 6 | M/34 | Sexual obsession, pathologic doubt, checking, reassurance seeking | None | 15/13 | Fluoxetine 180 mg, sertraline 100 mg, risperidone 7 mg, aripiprazole 10 mg, alprazolam 0.75 mg, clonazepam 0.5 mg, propranolol 40 mg, trihexine 4 mg | Sertraline 300 mg, fluoxetine, 80 mg, clomipramine 125 mg, olanzapine 10 mg |
| 7 | M/37 | Obsession with need for symmetry or exactness, intrusive nonviolent thought and image, obsession about mistakes, repeating, checking, ordering, counting | Schizotypal personality traits | 16/8 | Escitalopram 70 mg, risperidone 5 mg, lorazepam 1 mg, clonazepam 1 mg, alprazolam 0.25 mg, benztropine 2 mg, propranolol 60 mg, diazepam 4 mg | Fluoxetine 80 mg, paroxetine 60 mg, sertraline 300 mg, venlafaxine XR 150 mg, clomipramine 150 mg, haloperidol 10 mg, risperidone 6 mg |
| 8 | F/26 | Contamination fear, obsession about certain numbers, washing, counting, checking | None | 13/10 | Escitalopram 30 mg, sertraline 100 mg, risperidone 4 mg, imipramine 50 mg, clonazepam 0.5 mg, trihexine 2 mg | Clomipramine 100 mg, escitalopram 60 mg, venlafaxine XR 225 mg, risperidone 4 mg, aripiprazole 15 mg |
| 9 | F/40 | Aggressive obsession, obsession about responsibility, contamination fear, undoing, repeating, washing | None | 22/20 | Escitalopram 40 mg, fluoxetine 80 mg, aripiprazole 5 mg, clonazepam 0.5 mg | Fluoxetine 80 mg, escitalopram 50 mg, clomipramine 125 mg, sertraline 200 mg, olanzapine 20 mg, bronanserin 4 mg |
| 10 | F/42 | Contamination fear, obsession about mistakes, washing, checking | None | 11/10 | Sertraline 300 mg, escitalopram 10 mg, clomipramine 100 mg, risperidone 4 mg | Clomipramine 100 mg, fluoxetine 80 mg ziprasidone 100 mg, sertraline 200 mg |
| 11 | F/23 | Contamination fear, washing | Major depressive disorder | 9/6 | Sertraline 200 mg, escitalopram 20 mg, risperidone 4 mg, procyclidine 5 mg | Paroxetine 60 mg, sertraline 200 mg, risperidone 3 mg, clomipramine 100 mg |
F = female; M = male; OCD = obsessive–compulsive disorder; pt. = patient.