Group differences in diffusion measures of the tracts connecting the left thalamus and the left pars triangularis*
| Group; mean ± SD | Statistical tests† | Statistical tests‡ | ||||||
|---|---|---|---|---|---|---|---|---|
| Variables | Control (n = 27) | Insomnia disorder (n = 22) | t | df | pFDR | F | df | pFDR |
| Fractional anisotropy (10−3) | 520.32 ± 29.00 | 485.95 ± 43.76 | 2.913 | 45 | 0.022 | 8.647 | 1,43 | 0.02 |
| Radial diffusivity (10−3 mm2/s) | 458.58 ± 26.33 | 481.20 ± 39.63 | −1.337 | 44 | 0.25 | 0.897 | 1,42 | 0.47 |
| Axial diffusivity (10−3 mm2/s) | 1174.59 ± 42.90 | 1140.90 ± 47.29 | 2.316 | 46 | 0.05 | 5.895 | 1,44 | 0.038 |
| Trace (10−3 mm2/s) | 2.09 ± 0.67 | 2.10 ± 0.86 | −0.345 | 41 | 0.73 | 0.056 | 1,39 | 0.81 |
FDR = false discovery rate; SD = standard deviation.
↵* Diffusion measures 1.5 × interquartile range below Q1 (lower quartile) or above Q3 (upper quartile) were removed in all analyses.
↵† Group differences in each diffusion measure using Student’s t-test.
↵‡ Adjusted for age and sex; analysis of covariance was performed to reveal group differences in each diffusion measure.