Group differences in the structural variables of the left thalamus and the pars triangularis*
| Group; mean ± SD | Statistical tests† | Statistical tests‡ | ||||||
|---|---|---|---|---|---|---|---|---|
| Variables | Control (n = 27) | Insomnia disorder (n = 22) | t | df | pFDR | F | df | pFDR |
| Pars triangularis | ||||||||
| Volume, mm3 | 3107.10 ± 512.07 | 2802.36 ± 37.62 | 2.209 | 47 | 0.05 | 5.782 | 1,45 | 0.048 |
| Adjusted volume§ | 0.00239 ± 0.00048 | 0.00202 ± 0.00031 | 3.236 | 45.001 | 0.014 | 14.322 | 1,45 | 0.003 |
| Surface area, mm2 | 1322.78 ± 189.98 | 1189.45 ± 169.25 | 2.564 | 47 | 0.044 | 6.911 | 1,45 | 0.041 |
| Grey matter thickness, mm | 2.46 ± 0.15 | 2.46 ± 0.17 | 0.105 | 47 | 0.92 | 0.368 | 1,45 | 0.55 |
| Grey matter volume, mm3 | 3725.22 ± 592.80 | 3349.82 ± 460.49 | 2.431 | 47 | 0.044 | 4.406 | 1,45 | 0.06 |
| Thalamus | ||||||||
| Volume, mm3 | 8699.79 ± 1129.52 | 8402.70 ± 1101.21 | 0.926 | 47 | 0.42 | 1.099 | 1,45 | 0.35 |
| Adjusted volume§ | 0.00665 ± 0.00093 | 0.00605 ± 0.00061 | 2.158 | 45 | 0.05 | 4.62 | 1,43 | 0.058 |
FDR = false discovery rate; SD = standard deviation.
↵* Structural measures 1.5 × interquartile range below Q1 (lower quartile) or above Q3 (upper quartile) were removed in all analyses.
↵† Group differences in each diffusion measure using a Student’s t-test (for equal variance) or Welch’s t-test (for unequal variance).
↵‡ Adjusted for age and sex; analysis of covariance was performed to reveal group differences in structural variables.
↵§ Adjusted volume was defined as each region of interest volume divided by intracranial volume.