Table 4

Association between imputed alternative allele dosage of variants and phenotypes (Table 3), with and without exposure to the corresponding childhood environmental factors in the discovery sample^*

Variant	Ref	Alt	Childhood environmental factors	Exposed		Unexposed

				β	p value	β	p value
DSM-5 diagnostic criterion count, African Americans
rs10188036	T	C	Change in residence	−1.91	1.20 × E⁻⁸	0.96	0.16
del-13:61274071	AT	A	Household drinking and illicit drug use	−2.75	2.17 × E⁻⁸	−0.41	0.50
Membership likelihood for subtype 5, African Americans
del-1:15511771	CTG	C	Nontraditional parental care	0.23	4.99 × E⁻¹⁰	−0.05	0.34
rs149843442	G	A	Household tobacco use	0.23	1.04 × E⁻⁷	−0.05	0.50
rs114492924	C	T	Change in residence	0.27	2.32 × E⁻⁸	0.02	0.72
rs139389287	T	G	Household tobacco use	0.23	7.68 × E⁻⁸	−0.05	0.41
rs148834561	A	G	Household drinking and illicit drug use	0.26	1.07 × E⁻⁷	−0.03	0.57
del-17:80342628	AG	A	Change in residence	−0.07	3.55 × E⁻⁸	−0.01	0.53
rs75591854	G	A	Household tobacco use	0.25	1.22 × E⁻⁷	−0.06	0.52
			Change in residence	0.27	1.15 × E⁻⁷	0.04	0.59
rs75414569	T	C	Household tobacco use	0.14	2.61 × E⁻⁸	0.02	0.69
rs148009780	C	T	Change in residence	0.24	9.14 × E⁻⁸	−0.04	0.56
Membership likelihood for subtype 4, European Americans
rs71428385	G	A	Household tobacco use	0.14	8.38 × E⁻⁵	0.09	0.27
rs56337958	A	G	Traumatic experience	0.31	4.29 × E⁻⁸	0.02	0.64

Alt = alternative allele; Ref = reference allele.
↵* Results were obtained via 2 separate sets of main effect tests for the variants, using exposed and unexposed subsamples, respectively.