Participant demographic and clinical characteristics
| Characteristic | Healthy controls (n = 41) | OCD (n = 49)* | p value |
|---|---|---|---|
| Demographic characteristics | |||
| Age, mean ± SD | 35.07 ± 10.04 | 34.42 ± 12.07 | 0.86 |
| Male, n (%) | 19 (46) | 16 (32) | 0.51 |
| Clinical characteristics | |||
| Medication, yes/no | — | 31/18 | — |
| Comorbidities, n | — | 22 | — |
| Depression | — | 14 | — |
| Attention-deficit/hyperactivity disorder | — | < 5 | — |
| Generalized anxiety disorder | — | < 5 | — |
| Social anxiety disorder | < 5 | — | |
| Panic attacks | — | < 5 | — |
| Borderline personality disorder | — | < 5 | — |
| Mean age of OCD onset, yr (min/max) | — | 18.3 (7/58) | — |
| Y-BOCS total, mean ± SD | — | 20.95 ± 6.1 | — |
| Y-BOCS obsessions, mean ± SD | — | 10.65 ± 3.46 | — |
| Y-BOCS compulsions, mean ± SD | — | 10.30 ± 3.83 | — |
| OCI-R total, mean ± SD | — | 27 ± 10.19 | — |
| HAM-D, mean ± SD | — | 13.3 ± 5.46 | — |
HAM-D = Hamilton Rating Scale for Depression; OCD = obsessive–compulsive disorder; OCI-R = Obsessive–Compulsive Inventory–Revised; SD = standard deviation; Y-BOCS = Yale–Brown Obsessive Compulsive Scale.
↵* Populations of fewer than 5 have been rounded to protect participant privacy.