Table 1

Demographic and clinical characteristics of the sample

CharacteristicGroup; no. (%) or mean ± SD [range]
BD, n = 118Control, n = 86
Scan site
 Centre 124 (20.5)22 (25.6)
 Centre 253 (45.3)26 (30.2)
 Centre 340 (34.2)38 (44.2)
Male sex47 (40.2)41 (47.7)
Age at MRI, yr36.5 ± 10.4 [18–63]37.3 ± 11.22 [19–66]
Right-handedness110 (96.5)84 (97.7)
IQ*108.7 ± 10.58107.39 ± 10.06
Medication
 Lithium39 (33.3)
 Anticonvulsants64 (54.7)
 Antipsychotic52 (44.4)
 Antidepressant54 (46.2)
Age at onset, yr20.8 ± 8.0
YMRS score§2.6 ± 3.7
MADRS score§3.5 ± 5.4
HAMD-17 score9.9 ± 7.9
  • BD = bipolar disorder; HAMD-17= Hamilton Rating Scale for Depression; NART = National Adult Reading Test; MADRS = Montgomery–Asberg Depression Rating Scale; SD = standard deviation; YMRS = Young Mania Rating Scale.

  • * Assessed using the NART.

  • Recorded at centre 1.

  • Recorded at centre 2.

  • § Recorded at centre 3.