Table 2

Amygdala subfield volumes in CeA and BLA subregions

Subnuclei of interest	Subfield volume, mm³, mean ± SE		F	η_p²^*	Volume reduction, %^†	p value (unadjusted)

	OCD (n = 81)	Control (n = 93)
Left central nucleus	37 ± 1	42 ± 1	9.675	0.053	−11.9	0.002^‡
Left basolateral complex
Left lateral nucleus	623 ± 7	644 ± 6	4.871	0.027	−3.3	0.029^§
Left basal nucleus	432 ± 5	442 ± 5	1.823	0.010	−2.3	0.18
Left accessory basal nucleus	230 ± 3	246 ± 3	11.616	0.063	−6.5	0.001^§
Right central nucleus	39 ± 1	45 ± 1	14.869	0.079	−13.3	< 0.001^‡
Right basolateral complex
Right lateral nucleus	636 ± 8	662 ± 8	5.71	0.032	−3.9	0.018^§
Right basal nucleus	442 ± 6	461 ± 5	5.839	0.033	−4.1	0.017^§
Right accessory basal nucleus	244 ± 4	269 ± 3	24.752	0.125	−9.3	< 0.001^§

BLA = basolateral complex of the amygdala; CeA = central nucleus of the amygdala; OCD = obsessive–compulsive disorder; SE = standard error.
↵* 0.01 indicates small effect size, 0.06 indicates medium effect size, and 0.14 indicates large effect size.
↵† Percent volume reduction was calculated as (adjusted mean volume of patients with OCD) – (adjusted mean volume of healthy controls) / [adjusted mean volume of healthy controls] × 100%.
↵‡ Significance with a nominal threshold.
↵§ Significance after false discovery rate correction for multiple comparisons.