Phenotypic correlations between schizophrenia and regional brain activity (rph), and the decomposed sources of the correlations (rph-a, rph-c, rph-e) predicted by the ACE model
| Correlation (95% CI) | ||||
|---|---|---|---|---|
| Region | rph-a | rph-c | rph-e | rph |
| Whole brain | −0.01 (−0.40 to 0.15) | −0.20 (−0.29 to 0.18) | −0.04 (−0.07 to 0.00) | −0.25 (−0.38 to −0.13) |
| Grey matter | 0.01 (−0.40 to 0.18) | −0.22 (−0.30 to 0.20) | −0.04 (−0.07 to 0.00) | −0.25 (−0.38 to −0.12) |
| White matter | −0.05 (−0.29 to 0.18) | −0.10 (−0.26 to 0.19) | −0.03 (−0.06 to 0.02) | −0.18 (−0.30 to −0.04) |
| Right hippocampus | −0.01 (−0.27 to 0.18) | −0.20 (−0.28 to 0.02) | 0.00 (−0.05 to 0.05) | −0.21 (−0.34 to −0.08) |
| Left hippocampus | 0.12 (−0.19 to 0.25) | −0.25 (−0.28 to 0.06) | 0.01 (−0.00 to 0.18) | −0.12 (−0.23 to 0.02) |
CI = confidence interval; rph: = total phenotypic correlation; rph-a, rph-c, rph-e = phenotypic correlation due to additive genetic, shared environmental and specific environmental influence, respectively.