Table 3

Clusters where neural activation correlated with the risk factors under investigation for the 3 fMRI contrasts

		MNI coordinates^*

Predictor	Location^†	x	y	z	No. of voxels	Coefficient
Successful response inhibition
DRD4 genotype	Superior frontal gyrus, middle frontal gyrus	−26	24	54	1608	−7.36
Prenatal exposure to smoking	Superior frontal gyrus, anterior cingulate gyrus	−2	32	40	845	−8.83
Failed response inhibition
DRD4 genotype	Supramarginal gyrus, superior parietal lobule	−38	−34	54	697	−7.30
Prenatal exposure to smoking	Supramarginal gyrus, superior parietal lobule, postcentral gyrus	−52	−32	52	1079	9.35
Prenatal exposure to alcohol	Orbitofrontal cortex	−28	34	−16	735	8.66
Failed – successful response inhibition
DAT1 genotype	Cerebellar crus II	−24	80	−46	797	−7.32
DRD4 genotype	Lateral occipital cortex	56	−68	−16	1050	13.78
	Frontal pole, frontal medial cortex	−4	56	−22	801	10.73
Prenatal exposure to smoking	Supramarginal gyrus, superior temporal gyrus, postcentral gyrus	62	−24	28	1431	12.38
	Supramarginal gyrus, postcentral gyrus	−56	−38	34	1258	10.86

MNI = Montreal Neurological Institute.
↵* Coordinates are in millimetres and represent the centre of gravity of the cluster.
↵† The anatomic labels are according to the Harvard–Oxford atlas.