Table 2

Scanning methods and altered fractional anisotropy regions of the 15 studies included in this meta-analysis

StudyField, T (coil, channels)Acquisition voxel, mm3No. of directionsCoordinate systemNo. of coordinatesType of analysisSignificant change in FA
Arnold et al.131.5 (8)2.5 × 2.5 × 2.5300VBA
Choi et al.413 (12)2 × 2 × 2600VBA, TBSS
Han et al.263 (12)1.8 × 1.8 × 3.020MNI1TBSSDecrease observed in the body of the CC
Hayashi et al.423 (8)1.02 × 1.02 × 4250TBSS
Jia et al.223 (8)1 × 1 × 315MNI4VBABoth decreases and increases observed in the bilateral parietal lobe (subgyral), R frontal lobe (paracentral lobule) and R cerebellum (anterior lobe)
Korgaonkar et al.443 (8)1.72 × 1.72 × 2.5420TBSS
Lai and Wu283 (NA)2 × 2 × 230MNI2TBSSBoth decreases and increases observed in the L SLF and R anterior thalamic radiation
Ma et al.231.5 (birdcage)1.875 × 1.875 × 413Tal4VBABoth decreases and increases observed in the R middle frontal gyrus, L lateral occipitotemporal gyrus, subgyral white matter of the R parietal lobe and R angular gyrus
Olvet et al.273 (8)0.95 × 0.95 × 325MNI5TBSSBoth decreases and increases observed in the R body of the CC, L inferior fronto-occipital fasciculus, R anterior thalamic radiation, R inferior longitudinal fasciculus and R cingulum
Ouyang et al.151.5 (birdcage)1.875 × 1.875 × 413MNI6VBABoth decreases and increases observed in the bilateral medial frontal gyri, R subgyral frontal and temporal lobes, L middle frontal gyri and L cingulate gyrus
Tha et al.241.5 (NA)1.875 × 1.875 × 512MNI9VBABoth decreases and increases observed in the bilateral frontal gyrus, bilateral anterior limbs of the internal capsule and L putamen, mediodorsal nucleus of the R thalamus, anterior and superior aspect of bilateral cerebellar hemispheres
Wang et al.253 (NA)0.9375 × 0.9375 × 542MNI4VBADecreases observed in the R cuneus gyrus, and increases observed in the R thalamus, R postcentral gyrus and cerebellar vermis
Wu et al.291.5 (NA)0.94 × 0.94 × 413MNI3VBADecreases observed in the R SLF within the frontal lobe, R middle frontal and L inferior parietal lobe
Zhu et al.431.5 (NA)1.875 × 1.875 × 413MNI3TBSSDecreases observed in the L anterior limb of the internal capsule and R parahippocampal gyrus, and both decreases and increases observed in the L posterior cingulate cortex
Zuo et al.301.5 (NA)1 × 1 × 425MNI2TBSSDecreases observed in the L centre portion of the SLF and L premotor area (BA 6)
  • BA = Brodmann area; CC = corpus callosum; DTI = diffusion tensor imaging; FA = fractional anisotropy; L = left; MDD = major depressive disorder; MNI = Montreal Neurological Institute; NA = not available; R = right; Tal = Talairach; SLF = superior longitudinal fasciculus; TBSS = tract-based spatial statistics; VBA = voxel-based analysis.