Receptor agonist | Subunit | Composition | Ion permeability |
---|---|---|---|
NMDA | NR1A–H NR2A–D NR3A–B | The functional protein contains a dimer of NR1 or NR2, with or without an NR3 subunit | Ca2+, Na+ |
AMPA | GLUR1–4 | Heterotetrameric protein containing a dimer of GluR2 and a dimer of either GluR1, 3 or 4 | Na+, K+ |
Kainate | GLUR5–7 KA 1–2 | Heterotetrameric protein containing dimers of GluR5–7 with or without KA 1–2 | Na+, K+ |
AMPA = α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; NMDA = N-methyl-d-aspartate.