Table 2

Voxel-based morphometric differences between patients with borderline personality disorder and healthy controls in whole brain analysis

MNI peak voxel
Contrast; location of peak voxels*xyztp valuezCluster size, k
Controls > BPD
 Left hippocampus−26−30−46.670.0015.7559
 Vermis 102−42−406.340.0025.5225
 Left inferior parietal gyrus−30−82446.10.0055.3624
 Left middle temporal gyrus−58−7205.50.0364.9332
 Right hippocampus28−30−24.930.204.517
 Left superior parietal gyrus−26−72544.910.214.4819
 Left middle temporal gyrus−70−38−24.910.214.4846
 Left precentral gyrus−36−20604.840.264.4320
 Left paracentral lobe−22−26744.750.324.3658
 Right superior frontal gyrus28−10704.740.334.3510
 Left middle occipital gyrus−22−98104.740.334.3542
 Inferior triangular frontal part482664.640.424.2712
 —−2−6184.620.444.2525
 Left medial superior frontal gyrus−870164.280.783.9818
 Right postcentral gyrus26−34664.170.873.8922
 Right middle temporal gyrus46−50124.110.913.8512
 Right paracentral lobe10−40644.100.923.8343
 Right inferior occipital gyrus34−96−24.060.943.823
 Right caudate61864.020.963.7610
 Left inferior temporal gyrus−64−56−143.970.973.7311
 Left middle temporal gyrus−60−44−123.950.983.7132
 Left middle temporal pole−2212−383.890.993.6618
 Left postcentral lobe−58−8443.870.993.6416
 Right medial orbitofrontal gyrus1446−43.82> 0.993.610
 —−50−80−123.73> 0.993.5210
BPD > controls
Left putamen322206.210.0035.4486
Right Heschl422645.870.0115.227
Right putamen right321225.690.0195.07111
 Left supplementary motor area2−6505.300.074.7821
 Left cerebellum 7−20−70−425.130.114.6515
 Right middle frontal gyrus3424465.090.134.6212
 Left superior temporal gyrus−40−2825.080.134.6111
 Right middle cingulum86344.710.364.3214
 Left superior occipital gyrus−22−80324.180.873.941
 Left cerebellum 6−22−50−324.150.893.8720
 —16−50−303.880.993.6510
 —−6−50−243.86> 0.993.6410
 —4−36−423.85> 0.993.6270
 Left cerebellum−30−66−203.80> 0.993.5838
 Vermis 6/Vermis 4/54−66−103.66> 0.993.4718
  • BPD = borderline personality disorder; MNI = Montreal Neurological Institute.

  • * According to Automated Anatomic Labelling atlas.

  • p < 0.05, family-wise error–corrected in bold; all others p < 0.05, uncorrected.