Table 2

Fractional anistropy values in healthy controls and patients with major depressive disorder

Brain regionGroup; mean (SD)p value, uncorrected*
ControlsMDD
Anterior genu0.68 (0.03)0.64 (0.04)0.001
Middle genu0.55 (0.06)0.54 (0.05)0.63
Posterior genu0.52 (0.05)0.50 (0.06)0.11
Anterior body0.53 (0.06)0.53 (0.06)0.67
Posterior body0.57 (0.07)0.53 (0.07)0.044
Isthmus0.56 (0.06)0.54 (0.08)0.36
Anterior splenium0.64 (0.09)0.60 (0.08)0.11
Middle splenium0.69 (0.05)0.66 (0.06)0.040
Posterior splenium0.66 (0.04)0.66 (0.05)0.92

  • MDD = major depressive disorder; SD = standard deviation.

  • ↵* Bonferroni corrected.