Table 3

Optimal and chronically used stimulation parameters in patients undergoing subcallosal cingulate deep brain stimulation for treatment-resistant depression

Electrode; stimulationPatient 1Patient 2Patient 3Patient 4
Type of stimulationMonopolarMonopolarMonopolarMonopolar
Electrode contacts*†C+ 2−
C+ 5−		C+ 3−
C+ 4−		C+ 0−
C+ 4−/5−		C+ 2−/3−
C+ 4−/5−
Optimal stimulation parameters determined by 12-week optimization phase (blinded)2 V, 270 μs, 130 Hz2 V, 450 μs, 130 Hz2 V, 450 μs, 130 HzNot determined
Stimulation setting used in postoptimization phase (open label)3 V, 150 μs, 130 Hz3 V, 210 μs, 130 Hz2 V, 450 μs, 130 Hz5 V, 90 μs, 130 Hz

  • ↵* 0–3 for left brain and 4–7 for right brain, where 3 and 7 are most dorsal, and 0 and 4 are most ventral poles of deep-brain stimulation lead.

  • ↵† C+ neurostimulator case as anode and − electrode contact as cathode.