Side effects on optimized dose of phenothiazine*
| Side effects† | Treatment group; no. of patients | |
|---|---|---|
| Levomepromazine (n = 17) | Chlorpromazine (n = 14) | |
| Insomnia | 8 | 8 |
| Constipation | 6 | 2 |
| Drowsiness | 5 | 3 |
| Dry mouth | 5 | 3 |
| Fatigue | 4 | 0 |
| Hypotension‡ | 3 | 3 |
| Dizziness | 3 | 1 |
| Headache | 2 | 3 |
| Agitation | 1 | 3 |
↵* Side effects present in final week of subjects completing the study on levomepromazine (LMP) or chlorpromazine (CPZ) with or without benztropine.
↵† In addition to those listed, heartburn and nasal stuffiness were experienced by 1 patient on LMP and anxiety in 1 patient on CPZ. Galactorrhoa present at baseline persisted on LMP in 1 patient.
↵‡ Systolic blood pressure < 100 mm Hg on standing immediately after being recumbent.