Region | Brodmann area | Pixels activated | T88 coordinates, mm | Z score | ||
---|---|---|---|---|---|---|
x | y | z | ||||
Healthy control subjects (n = 12) | ||||||
Increase in blood flow | ||||||
L supplementary motor area | 6 | 179 | −7 | 7 | 52 | 5.1 |
L superior temporal gyrus | 22 | 853 | −57 | −17 | 5 | 4.5 |
R superior temporal gyrus | 22 | 27 | 50 | −27 | 2 | 3.4 |
Broca’s area | 44 | * | −52 | −1 | 23 | 4.5 |
L precentral gyrus | 4 | 141* | −41 | −16 | 36 | 4.5 |
R precentral gyrus | 4 | 68 | 47 | −7 | 22 | 4.5 |
Cerebellum | 220 | 0 | −56 | −11 | 3.7 | |
Decrease in blood flow | ||||||
R superior frontal gyrus | 19 | 238 | 40 | −79 | 27 | 4.6 |
R inferior temporal gyrus | −37 | 26 | 61 | −61 | −2 | 4.4 |
R middle frontal gyrus | 9 | 90 | 47 | 34 | 27 | 4.2 |
L occipital gyrus | 19 | 27 | −29 | −86 | 27 | 4.0 |
R superior frontal gyrus | 10 | 89 | 22 | 50 | 0 | 3.8 |
R middle frontal gyrus | 8 | 26 | 40 | 25 | 45 | 3.4 |
Patients with schizophrenia (n = 18) | ||||||
Increase in blood flow | ||||||
L superior temporal gyrus | 21,22 | 948* | −54 | −14 | 2 | 4.8 |
R superior temporal gyrus | 21 | 96 | 56 | −29 | −2 | 4.0 |
Wernicke’s area | 41 | * | −54 | −36 | 14 | 4.7 |
L precentral gyrus | 6 | 397 | −50 | −9 | 36 | 4.5 |
R > L supplementary motor area | 6 | 179 | 4 | 2 | 54 | 4.4 |
Cerebellum | 37 | 226 | 5 | −70 | −16 | 4.2 |
R inferior frontal gyrus | 47 | 147 | 50 | 18 | 2 | 4.0 |
Decrease in blood flow | ||||||
L precuneus | 18 | 92 | −20 | −65 | 27 | 4.9 |
R fusiform gyrus | 36 | 38 | 32 | −36 | −11 | 4.8 |
R precuneus | 7 | 402 | 4 | −54 | 40 | 4.8 |
R inferior occipital gyrus | 18 | 49 | 34 | −88 | −9 | 4.1 |
R medial frontal gyrus | 10 | 90 | 2 | 50 | −7 | 3.9 |
R occipital gyrus | 19 | 133 | 38 | −79 | 29 | 3.6 |
L middle frontal gyrus | 8 | 33 | −34 | 20 | 40 | 3.6 |
L = left; Look = control condition; R = right; Read = reading condition.
↵* denotes confluent area of activation.