Hippocampal volumes in patients with major depressive disorder and controls
| Group; mean (SD) normalized volume, mm3 | ||||
|---|---|---|---|---|
| Hippocampal region | MDD, n = 39 | MDD unmedicated, n = 23 | MDD medicated, n = 16 | Controls, n = 34 |
| Tail | ||||
| Left | 520 (107) | 507 (116) | 538 (95) | 578 (91) |
| Right | 532 (119) | 524 (130) | 543 (103) | 601 (78) |
| Body | ||||
| Left | 765 (126) | 724 (117) | 823 (119) | 739 (126) |
| Right | 795 (140) | 750 (135) | 859 (125) | 756 (129) |
| Head | ||||
| Left | 1463 (228) | 1476 (267) | 1443 (161) | 1481 (191) |
| Right | 1503 (206) | 1498 (242) | 1510 (146) | 1625 (207) |
| Total | ||||
| Left | 2747 (297) | 2707 (344) | 2805 (211) | 2798 (257) |
| Right | 2829 (312) | 2772 (349) | 2912 (236) | 2982 (244) |
| Intracranial volume, cm3 | 1402 (127) | 1419 (137) | 1378 (233) | 1382 (123) |
MDD = major depressive disorder; SD = standard deviation.