Table 2

Brain activity responses across regions of interest during the initial (first 21 seconds of the emotional block) and the sustained (final 21 seconds of the block) performance of the facial emotional recognition task

Response; brain region	Talairach coordinates			t^*	p_{FDR–corrected}
Early and late respon ses within each group
Healthy participants
Initial response
Right amygdala	18	−5	−15	5.55	< 0.001
Left amygdala	−20	−3	−13	5.36	< 0.001
Bilateral medial frontal gyrus (BA 6)	4	12	45	5.52	< 0.001
	−8	8	47	4.74	< 0.001
Left cingulate gyr us (BA 32)	−8	19	38	4.08	< 0.001
Left inferior pariet al cortex (BA 40)	−40	−40	44	2.72	0.009
Sustained response
Right amygdala	20	−7	−15	7.04	< 0.001
Left amygdala	−22	−3	−17	5.01	< 0.001
Bilateral medial frontal gyrus (BA 6)	4	10	46	6.26	< 0.001
	−8	8	47	5.32	< 0.001
Left inferior pariet al cortex (BA 40)	−40	−41	44	2.59	0.011
Schizophrenia patients
Initial response
Right amygdala	22	−5	−15	3.34	0.002
Left amygdala	−26	−5	−17	2.12	0.030
	−20	−3	−15	2.02	0.036
Bilateral medial frontal gyrus (BA 6)	−4	12	49	5.11	< 0.001
	6	10	47	4.98	< 0.001
Bilateral cingulate gyrus (BA 32)	−6	23	38	5.26	< 0.001
	10	23	38	1.90	0.045
Left inferior pariet al cortex (BA 40)	−42	−36	50	6.84	< 0.001
Left medial fronta l cortex (BA 10)	−16	55	6	2.21	0.024
Sustained response
Bilateral medial frontal gyrus (BA 6)	6	10	47	4.15	0.008
	−4	12	49	4.02	0.008
Left cingulate gyr us	−6	23	38	4.76	0.005
Left inferior pariet al cortex (BA 40)	−42	−36	50	3.80	0.008
Left medial fronta l cortex (BA 10)	−18	53	7	3.11	0.013
Left middle temporal gyrus (BA 21)	−50	−2	−16	2.56	0.024
Between-group comparison of initial and sustained responses
Healthy participants > s chizophrenia patients
Initial response	No significant clusters
Sustained response
Right amygdala	20	−6	−18	4.06	0.038
Left amygdala	−20	−2	−16	3.62	0.038
Schizophrenia patients > healthy participants
Initial response
Left inferior pariet al cortex (BA 40)	−38	−40	55	5.13	0.001
Left medial fronta l cortex (BA 10)	−16	55	6	3.36	0.005
Left middle temporal gyrus (BA 21)	−52	0	−16	4.52	0.001
Sustained response
Left inferior pariet al cortex (BA 40)	−36	−40	55	4.28	0.039
Left medial fronta l cortex (BA 10)	−15	57	12	3.32	0.045
Left middle temporal gyrus (BA 21)	−52	0	−16	3.50	0.045

FDR = false discovery rate; BA = Brodmann area.
↵* Early and late responses calculated with 13 degrees of freedom; between-group comparisons calculated with 26 degrees of freedom.