Table 2

Comparison of neurocognitive function between groups

VariableEarly-onset OCD (n = 49)Late-onset OCD (n = 52)Healthy controls (n = 103)Fp valuePost hoc tests
Visuospatial ability: construction and memory, mean ± SD
 RCFT copy17.63 ± 2.8718.52 ± 1.1518.39 ± 1.17F2,181 = 3.76< 0.05EO < LO*; EO < controls
 RCFT IR12.02 ± 3.9012.88 ± 3.0513.51 ± 2.73F2,181 = 3.40< 0.05EO < controls*
 RCFT DR12.31 ± 3.6312.44 ± 3.1713.11 ± 2.98F2,181 = 1.200.30NS
Verbal fluency, mean ± SD
 COWAT letter41.33 ± 9.5440.71 ± 12.8045.42 ± 9.96F2,180 = 3.87< 0.05LO < controls*
 COWAT category38.48 ± 8.1139.58 ± 9.1042.02 ± 8.72F2,180 = 2.870.06LO < controls
Executive function, organization, mean ± SD
 WAIS PA11.45 ± 1.9211.45 ± 2.2011.34 ± 1.93F2,200 = 0.080.93NS
 WAIS BD13.35 ± 2.4812.98 ± 2.6714.03 ± 2.42F2,200 = 3.35< 0.05LO < controls*
 RCFT organization5.90 ± 1.845.69 ± 1.916.39 ± 1.54F2,181 = 2.860.06LO < controls
Executive function, cognitive flexibility, mean ± SD
 IED errors17.62 ± 10.0019.08 ± 11.0713.07 ± 8.70F2,160 = 5.98< 0.01LO > controls**; EO > controls*
Decision-making, mean ± SD
 CGT decision-making0.91 ± 0.110.89 ± 0.140.92 ± 0.09F2,144 = 0.730.48NS
 CGT risk-taking0.55 ± 0.130.55 ± 0.140.58 ± 0.14F2,144 = 0.620.54NS
  • BD = block design; CGT = Cambridge Gambling Task; COWAT = Controlled Oral Word Association Test; DR = delayed recall; EO = early-onset OCD; IED = Intra-Extra Dimensional Set Shift; IR = immediate recall; LO = late-onset OCD; OCD = obsessive–compulsive disorder; NS = not significant; PA = picture arrangement; RCFT = Rey–Osterrieth Complex Figure Test; SD = standard deviation; WAIS = Wechsler Adult Intelligence Scale.

  • * p < 0.05.

  • ** p < 0.01.

  • p at trend level.