Table 2

Significant correlations* between clinical response and structural connectivity

Metric, regionCorrelation coefficientp valueSlope
Number of tracts, right caudal cingulate cortex0.410.025.46
Number of tracts, left posterior cingulate cortex0.400.025.42
Volume of tracts, right caudal cingulate cortex0.350.041329
Mean diffusivity, right caudal cingulate cortex0.430.010.01
  • dTot = total distance.

  • * p < 0.05, uncorrected.

  • Between the stimulation position in the left dorsolateral prefrontal cortex and the regions of interest in the cingulate cortex, represented by dTot, including p value and slope (Fig. 4).

  • Not all patients showed indirect connections between the stimulation site and the cingulate cortex.