Table 5

Regions that showed a significant^* negative correlation between symptom improvement and changes in blood oxygen level–dependent signal before and after antidepressant treatment among patients in the selective serotonin reuptake inhibitor group

		Talairach coordinate
Region of activation	Cluster size	x	y	z	t value	p_{FDR–corrected}
Right hippocampus	91^†	34	−6	−20	6.90	0.35
Left inferior frontal gyrus (BA 45)	141^†	−36	26	3	6.44	0.35
Left supplementary motor area (BA 6)	58	−13	−23	62	5.30	0.35

BA = Brodmann area; FDR = false discovery rate.
↵* Significant at p < 0.001 before FDR correction (cluster size > 24 voxels).
↵† Significant after correction for multiple comparisons (p < 0.05).