Regions showing significant structural covariance increases in patients with OCD compared with healthy controls
| MNI coordinates | |||||||
|---|---|---|---|---|---|---|---|
| Seed region | x | y | z | z-score (t value) | p value* | k | Anatomic location |
| Left VRP | −53 | 38 | −2 | 4.59 (4.63) | 0.018 | 24 | Left IFG |
| Right CMS | 12 | 42 | −6 | 4.79 (4.84) | 0.008 | 145 | vmPFC |
CMS = centromedial-superficial amygdala; IFG = inferior frontal gyrus; MNI = Montreal Neurological Institute; OCD = obsessive–compulsive disorder; vmPFC = ventromedial prefrontal cortex; VRP = ventro-rostral putamen.
↵* Family-wise error–corrected.