Table 1

Demographic and clinical characteristics of patients with major depressive disorder and controls

Group; mean (SD)*
CharacteristicReboxetine, n = 8Citalopram, n = 12Controls, n = 20
Age, yr, mean36.1 (10.8)42.4 (12.8)37.6 (10.8)
School education, yr10.5 (1.4)10.5 (1.2)10.8 (1.2)
Sex, female:male7:111:118:2
Age at onset, yr34.3 (12.0)30.9 (12.2)
Duration of illness, yr8.3 (6.4)5.2 (7.7)
No. of previous episodes1.3 (0.8)1.0 (1.3)
Logical IQ score98.6 (10.4)104.8 (13.5)
Trail Making Test20 Part A score34.8 (9.1)35.7 (16.5)
Trail Making Test20 Part B score80.6 (25.8)77.2 (31.6)
Before treatment
 HRSD score24.4 (4.7)23.4 (4.4)
 BDI score25.5 (8.1)25.5 (11.3)3.6 (8.3)
After treatment
 HRSD score8.8 (5.8)8.3 (6.3)
 BDI score16.3 (11.2)15.1 (12.1)
Treatment response, % change in HRSD score65.5 (16.5)66.2 (23.7)
No. of patients in remission after treatment (HRSD score < 7)46
  • BDI = Beck Depression Inventory;22 HRSD = Hamilton Rating Scale for Depression;18 IQ = intelligence quotient, SD = standard deviation.

  • * Unless otherwise indicated.

  • There were no significant differences (p > 0.05) between patients given citalopram and those given reboxetine.