Table 3

Regions that showed significant^* decreases in blood oxygen level–dependent signal after 6 weeks of antidepressant treatment

Group; before > after treatment for the incongruent condition	Cluster size	Talairach coordinate			t value	p_{FDR-corrected}
	Cluster size	x	y	z	t value	p_{FDR-corrected}
All patients
Left middle temporal gyrus (BA 21/22)	1152^†	−48	−24	−4	5.64	0.02
Right middle temporal gyrus (BA 22)	52	65	−33	0	3.95	0.04
Right insula (BA 13)	36	44	−27	0	3.84	0.04
Right inferior frontal gyrus (BA 47)	116	24	19	−16	4.55	0.02
Right superior parietal lobule (BA 7)	92	38	−55	58	3.62	0.06
Left superior parietal lobule (BA 7)	51	−12	−54	47	4.15	0.03
Left superior parietal lobule (BA 7)	28	−16	−61	64	3.92	0.04
Right inferior parietal lobule (BA 40)	78	48	−39	33	4.75	0.02
Right inferior parietal lobule (BA 40)	26	51	−42	54	3.92	0.04
Left cerebellum	45	−4	−47	−9	4.27	0.03
Citalopram
Right amygdala/Hippocampus	583^†	18	−12	−9	4.85	0.07
Left amygdala/Hippocampus		−18	−8	−8	4.6	0.07
Right inferior frontal gyrus (BA 47)	154	24	19	−16	4.64	0.07
Right middle frontal gyrus (BA 6)	85	46	8	44	3.71	0.07
Left middle frontal gyrus (BA 6)	141^†	−42	2	48	4.41	0.07
Right superior frontal gyrus (BA 6)	51	10	15	64	4.47	0.07
Right medial frontal gyrus (BA 6)	34	14	6	49	3.88	0.07
Left middle temporal gyrus (BA 22)	134	−59	−37	−3	4.09	0.07
Right superior temporal gyrus (BA 21)	37	48	−20	−7	4.00	0.07
Left superior temporal gyrus (BA 21)	110	−46	−23	−2	4.07	0.07
Right superior parietal lobule (BA 7)	85	22	−67	57	4.08	0.07
Right superior parietal lobule (BA 7)	73	14	6	49	3.77	0.07
Right superior parietal lobule (BA 7)	25	26	−52	50	3.65	0.07
Left superior parietal lobule (BA 7)	261^†	−16	−61	64	4.29	0.07
Right inferior parietal lobule (BA 40)	72	51	−40	54	4.33	0.07
Left inferior parietal lobule (BA 40)	188^†	−38	−48	54	4.09	0.07
Left cerebellum	39	−4	−47	−9	3.76	0.07
Reboxetine
Left middle temporal gyrus (BA 21)	151^†	−38	−52	6	4.66	0.19
Left superior temporal gyrus (BA 22)	136	−51	−25	−2	4.39	0.19
Left parahippocampal gyrus (BA 30)	75	−22	−37	0	3.94	0.19

BA = Brodmann area; FDR = false discovery rate.
↵* Significant at p < 0.001 before FDR correction (cluster size > 24 voxels).
↵† Significant after correction for multiple comparisons (p < 0.05).