Clinical outcome measures
| Period; mean ± SD (range) | |||||
|---|---|---|---|---|---|
| Measure | Pre-ECT | Post-ECT | Changes; mean ± SD (range) | t27 | p value |
| MADRS | 35.04 ± 6.88 (22–50) | 9.61 ± 11.47 (0–44) | 25.43 ± 11.05 (−8 to 45) | 12.18 | < 0.001 |
| MMSE | 23.64 ± 4.54 (12–30) | 26.32 ± 3.44 (18–30) | −2.68 ± 3.83 (−14 to 6) | −3.70 | 0.001 |
| CORE total | 17.64 ± 8.17 (3–35) | 4.96 ± 5.00 (0–20) | 12.68 ± 8.60 (−3 to 31) | 7.80 | < 0.001 |
| CORE cluster noninteraction | 6.36 ± 4.06 (0–16) | 1.54 ± 1.87 (0–7) | 4.82 ± 4.43 (−1 to 16) | 5.76 | < 0.001 |
| CORE cluster agitation | 3.79 ± 3.14 (0–11) | 0.89 ± 1.57 (0–7) | 2.89 ± 3.02 (−1 to 9) | 5.06 | < 0.001 |
| CORE cluster retardation | 7.5 ± 3.73 (1–17) | 2.54 ± 2.64 (0–9) | 4.96 ± 3.30 (−2 to 11) | 7.95 | < 0.001 |
ECT = electroconvulsive therapy; MADRS = Montgomery–Åsberg Depression Rating Scale; MMSE = Mini Mental State Examination; SD = standard deviation.