Linear regression analyses for COMT Val158Met polymorphism on hyperactivity/inattention scores from the Strengths and Difficulties Questionnaire according to sex
| Sex | Age, yr | Genotype | n | SDQ score, mean ± SD | β coefficient | t | p value | R2 |
|---|---|---|---|---|---|---|---|---|
| Male | 11 | Met/Met | 363 | 4.45 ± 3.15 | 0.043 | 1.908 | 0.06 | 0.012 |
| Met/Val | 937 | 4.84 ± 3.08 | ||||||
| Val/Val | 653 | 4.95 ± 3.08 | ||||||
| 15 | Met/Met | 364 | 3.87 ± 3.04 | 0.030 | 1.305 | 0.19 | 0.005 | |
| Met/Val | 938 | 4.37 ± 3.13 | ||||||
| Val/Val | 654 | 4.27 ± 3.19 | ||||||
| Female | 11 | Met/Met | 396 | 3.86 ± 2.94 | −0.004 | −0.167 | 0.87 | 0.002 |
| Met/Val | 962 | 3.80 ± 3.02 | ||||||
| Val/Val | 687 | 3.85 ± 3.07 | ||||||
| 15 | Met/Met | 395 | 3.22 ± 2.72 | 0.013 | 0.609 | 0.54 | 0.003 | |
| Met/Val | 963 | 3.47 ± 2.97 | ||||||
| Val/Val | 688 | 3.40 ± 2.92 |
SD = standard deviation; SDQ = Strengths and Difficulties Questionnaire.