Table 1

The results of polygenic scoring profile analysis

TargetpT value*No. SNPs†AUC (95% CI)pAUC value
Schizophrenia< 0.0011890.52 (0.48–0.55)0.16
Schizophrenia< 0.0510 6160.53 (0.50–0.56)0.036
Schizophrenia< 0.121 6850.54 (0.51–0.58)0.004
Schizophrenia< 0.5110 3290.53 (0.50–0.56)0.042
Schizophrenia≤ 0.99222 1610.53 (0.50–0.56)0.032
Psoriasis< 0.0011820.51 (0.48–0.53)0.25
Psoriasis< 0.0511 3760.53 (0.51–0.56)0.004
Psoriasis< 0.122 9270.54 (0.52–0.56)< 0.001
Psoriasis< 0.5112 6450.54 (0.52–0.57)< 0.001
Psoriasis≤ 0.99222 1610.54 (0.51–0.56)0.002

  • AUC = area under the receiver operating characteristics curve; CI = confidence interval; SNP = single nucleotide polymorphism.

  • ↵* Threshold of association p value in the discovery set.

  • ↵† Number of SNPs with a p value in the discovery set.