Table 2

Dynamic causal modelling parameters from the best fitting model

Group; mean ± SD*
ConnectivityControl
n = 19
FEP, treated
n = 12
FEP, untreated
n = 17
Right insula– ACC0.1867 ± 0.30640.0651 ± 0.1567−0.0642 ± 0.2877
Left insula– ACC0.0976 ± 0.31380.1182 ± 0.22340.1879 ± 0.4933
  • ACC = anterior cingulate cortex; FEP = first-episode psychosis; SD = standard deviation.

  • * Modulatory effect induced by high-probability reward cues.

  • F2,47 = 3.823, p = 0.029 for analysis of variance, and p = 0.025 (healthy controls > untreated FEP) for Bonferroni-corrected post hoc t test.

  • Significant t tests within each group compared with 0 (p < 0.05).