Table 2

Patients with major psychiatric disorders who showed significant correlations between fractional anisotropy in white matter and NRG1-β1*

IndexWhite matter labelCluster size, voxelsMNI coordinates, x, y, zR
White matter AGenu of corpus callosum, right external capsule, right uncinate fasciculus, right inferior fronto-occipital fasciculus28326, 12, 4−0.312
White matter BFornix, right optic tract18314, −2, 16−0.307
White matter CLeft inferior fronto-occipital fasciculus, left straight gyrus white matter, left olfactory radiation161−14, 18, −18−0.269
  • MNI = Montreal Neurological Institute; NRG1 = neuregulin 1.

  • * Significance was set at p < 0.005 at the voxel level, with Gaussian random field correction for cluster-level inference of p < 0.05.