Participant baseline characteristics
| Characteristic | HCV-treated | HCV-untreated | HCV-uninfected | p value | ||
|---|---|---|---|---|---|---|
| HCV-treated v. HCV-untreated | HCV-treated v. HCV-uninfected | HCV-untreated v. HCV-uninfected | ||||
| Participants | 8931 | 17862 | 17862 | |||
| Sex | ||||||
| Male | 4810 (53.86) | 9620 (53.86) | 9620 (53.86) | > 0.99 | > 0.99 | > 0.99 |
| Female | 4121 (46.14) | 8242 (46.14) | 8242 (46.14) | |||
| Mean age, yr | 50.22 ± 10.61 | 50.33 ± 11.11 | 49.72 ± 11.72 | |||
| Age range, yr | ||||||
| 20–39 | 1535 (17.19) | 3070 (17.19) | 3070 (17.19) | > 0.99 | > 0.99 | > 0.99 |
| 40–49 | 2473 (27.69) | 4946 (27.69) | 4946 (27.69) | |||
| 50–59 | 3242 (36.30) | 6484 (36.30) | 6484 (36.30) | |||
| ≥ 60 | 1681 (18.82) | 3362 (18.82) | 3362 (18.82) | |||
| NHI registration location | ||||||
| Urban | 2169 (24.29) | 4338 (24.29) | 4338 (24.29) | > 0.99 | > 0.99 | > 0.99 |
| Township | 2755 (30.85) | 5510 (30.85) | 5510 (30.85) | |||
| Rural | 4007 (44.87) | 8014 (44.87) | 8014 (44.87) | |||
| Charlson Comorbidity Index score | ||||||
| 0 | 4244 (47.52) | 8488 (47.52) | 8488 (47.52) | > 0.99 | > 0.99 | > 0.99 |
| 1 | 2992 (33.50) | 5984 (33.50) | 5984 (33.50) | |||
| ≥ 2 | 1695 (18.98) | 3390 (18.98) | 3390 (18.98) | |||
| Index year | ||||||
| 2003–2006 | 4348 (48.68) | 8696 (48.68) | 8696 (48.68) | > 0.99 | > 0.99 | > 0.99 |
| 2007–2009 | 2775 (31.07) | 5550 (31.07) | 5550 (31.07) | |||
| 2010–2012 | 1808 (20.24) | 3616 (20.24) | 3616 (20.24) | |||
| Baseline risk factor | ||||||
| Liver cirrhosis | 965 (10.81) | 1071 (6.00) | 7 (0.04) | < 0.001 | < 0.001 | < 0.001 |
| Chronic obstructive pulmonary disease | 1033 (11.57) | 2094 (11.72) | 1733 (9.70) | 0.70 | < 0.001 | < 0.001 |
| End-stage renal disease | 60 (0.67) | 499 (2.79) | 41 (0.23) | < 0.001 | < 0.001 | < 0.001 |
| Diabetes mellitus | 1673 (18.73) | 4071 (22.79) | 3254 (18.22) | < 0.001 | 0.30 | < 0.001 |
| Hypertension | 2634 (29.49) | 6315 (35.35) | 4970 (27.82) | < 0.001 | 0.004 | < 0.001 |
| Dyslipidemia | 1095 (12.26) | 3640 (20.38) | 3211 (17.98) | < 0.001 | < 0.001 | < 0.001 |
| Cardiovascular events | 227 (2.54) | 729 (4.08) | 480 (2.69) | < 0.001 | 0.48 | < 0.001 |
| Stroke | 299 (3.35) | 944 (5.28) | 878 (4.92) | < 0.001 | < 0.001 | 0.11 |
HCV = hepatitis C virus.
Values are n (%) or mean ± standard deviation.