Characteristic | Autism spectrum disorder† n = 88 | Typically developing controls† n = 51 | F / χ2 / t | p value | qFDR | Cohen d |
---|---|---|---|---|---|---|
Age, yr (range) | 12.68 ± 3.09 (8–20) | 13.73 ± 3.61 (8–20) | F = 3.24 | 0.07 | – | – |
Male, n (%) | 84 (95.5) | 45 (88.2) | χ2 = 2.52 | 0.11 | – | – |
Left-handedness, n (%) | 80 (90.9) | 48 (94.1) | χ2 = 0.46 | 0.50 | – | |
Full-scale IQ | 104 ± 16 | 113 ± 12 | F = 13.51 | < 0.001 | – | – |
Cortical thickness, mm | ||||||
Right hemisphere | 3.101 ± 0.169 | 3.157 ± 0.100 | t = −2.65 | 0.009 | – | 0.403 |
Left hemisphere | 3.108 ± 0.165 | 3.158 ± 0.107 | t = −2.50 | 0.014 | – | 0.360 |
Right middle-posterior part of the cingulate gyrus and sulcus (posterior midcingulate cortex) | 3.383 ± 0.223 | 3.498 ± 0.169 | t = −3.61 | < 0.001 | 0.004 | 0.581 |
Right posterior transverse collateral sulcus | 2.730 ± 0.285 | 2.855 ± 0.246 | t = −3.39 | 0.001 | 0.004 | 0.470 |
Right orbital gyri | 3.399 ± 0.219 | 3.500 ± 0.159 | t = −2.93 | 0.004 | 0.008 | 0.528 |
Right superior segment of the circular sulcus of the insula | 3.424 ± 0.227 | 3.508 ± 0.169 | t = −3.22 | 0.002 | 0.005 | 0.420 |
Right posterior ramus of the lateral sulcus | 3.181 ± 0.239 | 3.294 ± 0.194 | t = −2.76 | 0.007 | 0.008 | 0.519 |
Right triangular part of the inferior frontal gyrus | 3.281 ± 0.265 | 3.380 ± 0.197 | t = −2.82 | 0.006 | 0.008 | 0.424 |
Right superior temporal sulcus (parallel sulcus) | 3.156 ± 0.202 | 3.222 ± 0.165 | t = −2.73 | 0.007 | 0.008 | 0.358 |
Right orbital part of the inferior frontal gyrus | 3.409 ± 0.301 | 3.521 ± 0.226 | t = −2.90 | 0.004 | 0.008 | 0.421 |
Right lateral occipitotemporal gyrus (fusiform gyrus, O4–T4) | 3.408 ± 0.211 | 3.504 ± 0.179 | t = −2.61 | 0.010 | 0.010 | 0.491 |