Participant demographic and clinical characteristics
| Characteristic | rds-ccPAS-1500 (n = 13) | rds-ccPAS-750 (n = 9) | ss-PFC (n = 14) | ss-PPC (n = 14) | F or χ2 | p value |
|---|---|---|---|---|---|---|
| Age, yr, mean ± SD | 40.15 ± 13.23 | 40.56 ± 9.30 | 40.71 ± 9.67 | 42.14 ± 6.98 | 0.129 | 0.94 |
| Male, n (%) | 3 (23.1) | 5 (55.6) | 6 (42.9) | 5 (35.7) | 2.577 | 0.46 |
| Education, yr, median (IQR) | 13.00 (11.00–13.00) | 13.00 (13.00–15.00) | 13.00 (10.25–15.00) | 15.00 (13.00–15.00) | 4.563 | 0.21 |
| Employed, n (%) | 12 (92.3) | 9 (100) | 14 (100) | 13 (92.9) | 1.780 | 0.62 |
| Taking medication, n (%) | 3 (23.1) | 1 (11.1) | 7 (50.0) | 2 (14.3) | 6.284 | 0.01 |
| CGI-S, median (IQR) | 5.00 (4.00–6.00) | 5.00 (4.50–5.50) | 5.00 (4.00–6.00) | 5.00 (4.00–5.00) | 1.164 | 0.76 |
| HAM-A score, mean ± SD | 23.2 ± 5.4 | 23.2 ± 3.9 | 22.1 ± 4.8 | 21.9 ± 4.9 | 0.272 | 0.85 |
| HAM-D score, mean ± SD | 15.1 ± 4.1 | 15.1 ± 3.8 | 14.2 ± 3.2 | 14.6 ± 4.6 | 0.145 | 0.93 |
| PSQI score, mean ± SD | 12.0 ± 3.9 | 12.0 ± 3.7 | 12.5 ± 3.3 | 11.9 ± 3.8 | 0.70 | 0.98 |
| RMT, mean ± SD | 41.5 ± 5.5 | 41.4 ± 6.6 | 45.4 ± 5.7 | 42.4 ± 4.8 | 1.52 | 0.22 |
CGI-S = Clinical Global Impression–Severity; HAM-A = Hamilton Anxiety Rating Scale; HAM-D = Hamilton Depression Rating Scale; IQR = interquartile range; PSQI = Pittsburgh Sleep Quality Index; rds-ccPAS-750 = repetitive dual-site cortical-cortical paired associative stimulation, 750 pulses per session; rds-ccPAS-1500 = repetitive dual-site cortical-cortical paired associative stimulation, 1500 pulses per session; RMT = resting motor threshold; SD = standard deviation; ss-PFC = single-site stimulation over the dorsolateral prefrontal cortex; ss-PPC = single-site stimulation over the right posterior parietal cortex.