Table 2

Global properties of morphology covariance networks constructed from the Destrieux Atlas*

MeasurePatients with first-episode MDD
n = 76
Healthy controls
n = 66
p value
Thickness-based network
 Local efficiency
  Original0.8070.7920.24
  Random-null0.687 ± 0.0060.687 ± 0.006
 Global efficiency
  Original0.6710.6920.021
  Random-null0.801 ± 0.0080.803 ± 0.008
 Targeted attack
  Original66.2270.740.027
  Random-null70.40 ± 1.4270.51 ± 1.40
 Random attack
  Original71.6173.160.007
  Random-null72.78 ± 0.3672.79 ± 0.38
Surface area–based network
 Local efficiency
  Original0.7590.7590.94
  Random-null0.762 ± 0.0050.762 ± 0.006
 Global efficiency
  Original0.6950.6950.74
  Random-null0.695 ± 0.00030.695 ± 0.0003
 Targeted attack
  Original73.3472.990.29
  Random-null73.01 ± 0.2573.02 ± 0.26
 Random attack
  Original73.3873.370.65
  Random-null73.37 ± 0.2473.38 ± 0.24
Gyrification-based network
 Local efficiency
  Original0.8340.8230.37
  Random-null0.825 ± 0.0080.820 ± 0.009
 Global efficiency
  Original0.6890.6900.70
  Random-null0.690 ± 0.0020.690 ± 0.002
 Targeted attack
  Original71.0072.000.37
  Random-null71.58 ± 0.8971.50 ± 0.97
 Random attack
  Original73.2173.270.57
  Random-null73.20 ± 0.1173.19 ± 0.13
  • MDD = major depressive disorder.

  • * Global properties (averaged local efficiency and global efficiency) and resilience (targeted attack and random attack) of the 3 morphology covariance networks (thickness-based, surface area–based and gyrification-based) are presented. Values are mean ± standard deviation.