Correlation between the Hamilton Depression Rating Scale (17 items) and functional near-infrared spectroscopy findings during assessment of finger tapping
| Patient group, task | Area of the brain (fNIRS channel) | Pearson correlation | p value |
|---|---|---|---|
| Healthy controls | |||
| Finger tapping | Right VLPFC (channel 3) | 0.474 | 0.02 |
| Left motor area (channel 17) | 0.452 | 0.03 | |
| Verbal fluency | Right motor area (channel 18) | −0.426 | 0.04 |
| Dual task | – | – | – |
| Patients without TRD | |||
| Finger tapping | Right VLPFC (channel 4) | 0.490 | 0.02 |
| Right VLPFC (channel 14) | 0.481 | 0.03 | |
| Right DLPFC (channel 15) | 0.591 | 0.005 | |
| Verbal fluency | Left DLPFC (channel 5) | −0.533 | 0.009 |
| Left motor area (channel 17) | −0.697 | 0.001 | |
| Dual task | Left VLPFC (channel 10) | 0.518 | 0.02 |
| Patients with TRD | |||
| Finger tapping | – | – | – |
| Verbal fluency | Right motor area (channel 18) | −0.511 | 0.03 |
| Dual task | Right DLPFC (channel 7) | −0.485 | 0.03 |
DLPFC = dorsolateral prefrontal cortex; fNIRS = functional near-infrared spectroscopy; TRD = treatment-resistant depression; VLPFC = ventrolateral prefrontal cortex.