Table 3

Correlation between the Hamilton Depression Rating Scale (17 items) and functional near-infrared spectroscopy findings during assessment of finger tapping

Patient group, taskArea of the brain (fNIRS channel)Pearson correlationp value
Healthy controls
 Finger tappingRight VLPFC (channel 3)0.4740.02
Left motor area (channel 17)0.4520.03
 Verbal fluencyRight motor area (channel 18)−0.4260.04
 Dual task
Patients without TRD
 Finger tappingRight VLPFC (channel 4)0.4900.02
Right VLPFC (channel 14)0.4810.03
Right DLPFC (channel 15)0.5910.005
 Verbal fluencyLeft DLPFC (channel 5)−0.5330.009
Left motor area (channel 17)−0.6970.001
 Dual taskLeft VLPFC (channel 10)0.5180.02
Patients with TRD
 Finger tapping
 Verbal fluencyRight motor area (channel 18)−0.5110.03
 Dual taskRight DLPFC (channel 7)−0.4850.03
  • DLPFC = dorsolateral prefrontal cortex; fNIRS = functional near-infrared spectroscopy; TRD = treatment-resistant depression; VLPFC = ventrolateral prefrontal cortex.