Table 2

Subgroup analysis of factors affecting therapeutic benefits of NF for symptoms of inattention, hyperactivity/impulsivity, and global symptoms in individuals with ADHD (Hedges g)

Symptom; groupDistal raterMost proximal rater
ng*95 % CIZQp valueng*95 % CIZQp value
Inattention
EEG-NF
 SCP30.26−0.08 to 0.601.521.470.0430.06−0.54 to 0.650.193.680.001
 θ/β (or SMR) ratio70.11−0.08 to 0.311.17120.22−0.07 to 0.511.47
 Combining 2 protocols30.53−0.23 to 1.291.3830.580.26 to 0.913.50§
Control
 TAU/wait list50.390.08 to 0.692.45§1.770.0380.510.26 to 0.764.00§7.87§0.004
 Sham/placebo NF20.08−0.19 to 0.390.653−0.03−0.31 to 0.25−0.19
Hyperactivity/impulsivity
EEG-NF
 SCP30.11−0.12 to 0.330.930.250.1030.05−0.30 to 0.400.291.210.03
 θ/β (or SMR) ratio70.11−0.13 to 0.340.9190.14−0.04 to 0.321.51
 Combining 2 protocols20.21−0.16 to 0.581.1330.31−0.02 to 0.631.86
Control
 TAU/wait list4−0.16−0.39 to 0.720.580.140.6040.26−0.01 to 0.541.880.230.03
 Sham/placebo NF20.04−0.25 to 0.340.3030.17−0.11 to 0.451.17
Global
EEG-NF
 SCP30.16−0.09 to 0.411.280.160.0440.23−0.16 to 0.621.171.590.003
 θ/β (or SMR) ratio60.21−0.011 to 0.521.2970.22−0.09 to 0.531.39
 Combining 2 protocols20.28−0.26 to 0.821.0120.510.14 to 0.882.70§
Control
 TAU/wait list40.17−0.04 to 0.381.580.520.1540.440.15 to 0.733.01§2.420.01
 Sham/placebo NF20.04−0.25 to 0.330.2620.12−0.18 to 0.410.78
  • ADHD = attention-deficit/hypheractivity disorder; CI = confidence interval; EEG-NF = electroencephalographic biofeedback; NF = neurofeedback; SCP = slow cortical potential; SMR = sensorimotor rhythm; TAU = treatment as usual.

  • * According to the random effects model.

  • Cochran Q for assessing heterogeneity based on random effects analysis.

  • Significance of difference in effect sizes between subgroups.

  • § p < 0.05.