Comparisons of neuroelectrophysiological measurements
| Measure | Mean ± SD | F | p | FES v. HC | BD v. HC | MDD v. HC | BD v. FES | MDD v. FES | BD v. MDD | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FES n = 53 | BD n = 30 | MDD n = 25 | HC n = 82 | Total n = 190 | p | d | p | d | p | d | p | d | p | d | p | d | |||
| Habituation, % | 10.90 ± 31.79 | 9.26 ± 44.23 | 18.51 ± 23.86 | 13.40 ± 41.24 | 12.78 ± 37.04 | 0.32 | 0.81 | 1.00 | 0.07 | 1.00 | 0.09 | 1.00 | 0.15 | 1.00 | 0.04 | 1.00 | 0.27 | 1.00 | 0.26 |
| Latency, ms | 174.53 ± 65.98 | 228.92 ± 79.87 | 203.08 ± 107.8 | 158.51 ± 97.94 | 178.74 ± 91.68 | 4.71 | 0.003 | 1.00 | 0.19 | 0.004 | 0.78 | 0.18 | 0.17 | 0.08 | 0.74 | 1.00 | 0.31 | 1.00 | 0.27 |
| SR, μV | 67.91 ± 35.14 | 55.59 ± 27.44 | 63.96 ± 37.83 | 65.74 ± 30.96 | 64.51 ± 32.63 | 1.11 | 0.35 | 1.00 | 0.06 | 0.56 | 0.34 | 1.00 | 0.05 | 0.96 | 0.39 | 1.00 | 0.11 | 0.80 | 0.25 |
| PSC-PPI, % | 21.53 ± 27.20 | 21.55 ± 27.59 | 29.08 ± 28.73 | 29.44 ± 21.62 | 25.93 ± 25.29 | 1.48 | 0.22 | 0.46 | 0.32 | 0.89 | 0.31 | 1.00 | 0.01 | 1.00 | 0.00 | 1.00 | 0.26 | 1.00 | 0.26 |
| PSS-PPI, % | 22.88 ± 24.30 | 30.70 ± 29.87 | 37.52 ± 29.31 | 42.11 ± 17.41 | 34.32 ± 24.59 | 7.61 | < 0.001 | < 0.001 | 0.90 | 0.15 | 0.46 | 1.00 | 0.19 | 0.89 | 0.28 | 0.06 | 0.54 | 1.00 | 0.23 |
BD = bipolar disorder; FES = first-episode schizophrenia; HC = healthy control; MDD = major depressive disorder; PSC-PPI = perceived spatial co-location paradigm of prepulse inhibition; PSS-PPI = perceived spatial separation paradigm of prepulse inhibition; SD = standard deviation; SR = startle reflex.