Regular ArticleCytochrome P4502E (CYP2E) in Brain: Constitutive Expression, Induction by Ethanol and Localization by Fluorescence in Situ Hybridization☆
References (27)
- et al.
Brain Res.
(1993) - et al.
Anal. Biochem.
(1990) Anal. Biochem.
(1976)- et al.
J. Biol. Chem.
(1986) - et al.
Biochem. Biophys. Res. Commun.
(1997) - et al.
Biochem. Pharmacol.
(1998) - et al.
Biochem. Pharmacol.
(1995) - de Montellano, O. 1986, Cytochrome P450: Structure, Mechanism and Biochemistry, Plenum, New...
- et al.
Annu. Rev. Pharmacol. Toxicol.
(1986) - et al.
J. Natl. Can. Inst.
(1990)
Drug Metab. Rev.
(1995)
Physiol. Rev.
(1997)
J. Neurochem.
(1966)
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2022, Advances in PharmacologyCitation Excerpt :Of note, CYP2E1 is also induced in the liver, while CYP2D is not (Howard, Micu, Sellers, & Tyndale, 2001; Yue et al., 2008). Ethanol pretreatment also increases CYP2D and CYP2E1 protein in the rat brain, as well as inducing CYP2E1 in the rat liver (Upadhya, Tirumalai, Boyd, Mori, & Ravindranath, 2000; Warner & Gustafsson, 1994; Yue et al., 2009). CYP2B1 is induced by daily nicotine pretreatments in the rat brain and liver, although mRNA is also increased suggesting that transcriptional regulation may be involved (Miksys, Hoffmann, et al., 2000; Yue et al., 2009).
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This research was supported by National Institutes of Health Grant MH55494.
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