Elsevier

Biological Psychiatry

Volume 37, Issue 11, 1 June 1995, Pages 789-797
Biological Psychiatry

Original article
Asymmetrical visual-spatial attentional performance in ADHD: Evidence for a right hemispheric deficit

https://doi.org/10.1016/0006-3223(94)00217-QGet rights and content

This study was designed to confirm the presence of a lateralizing deficit in visual-spatial attention in children with ADHD, to further characterize the nature of this deficit and to specify the likely hemispheric locus of dysfunction. Two versions of the covert orienting of attention procedure which evaluated separately endogenous and exogenous cuing effects were administered to 20 unmedicated children aged 9–12 with ADHD and 20 matched controls. Both groups also underwent thorough psychiatric assessment and testing using the TOVA and the Wisconsin Card Sorting Task (WCST). Children with ADHD showed an asymmetrical performance deficit characterized by a loss of costs on controlled (endogenous) attentional orienting to invalidly cued left visual field targets. The degree of cost asymmetry correlated negatively with the number of categories sorted on the WCST. It was concluded that unmedicated children with ADHD show an asymmetrical performance deficit on the covert orienting procedure characterized by a disruption of right hemispheric attentional mechanisms. This deficit may be related to diminished right hemispheric frontal-striatal catecholamine activity.

References (31)

  • ConnorsCK

    Rating scales for use in drug studies with children

    Psychopharmacol Bull

    (1973)
  • DenklaMB

    Revised neurological examination for subtle signs

    Psychopharmacol Bull

    (1985)
  • EgleyR et al.

    Reflexive and voluntary orienting in detection and discrimination tasks

  • Goldman-RakicPS

    Circuitry of primate prefrontal cortex and regulation of behavior by representational memory

  • HeilmanKM et al.

    A possible pathophysiological substrate of attention deficit hyperactivity disorder

    J Child Neurol

    (1991)
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