Elsevier

Psychiatry Research

Volume 20, Issue 2, February 1987, Pages 97-105
Psychiatry Research

Measurement of lactate-induced panic and anxiety

https://doi.org/10.1016/0165-1781(87)90002-3Get rights and content

Abstract

Acute Panic Inventory (API) scores were obtained from 26 normal controls and 89 patients with either panic disorder or agoraphobia with panic attacks before and during lactate infusions. Retrospective ratings of the patients' usual spontaneous attacks were much higher, by API, than ratings of moments of severe stress by the controls. Point of panic API scores, as well as increments of panic scores over prelactate scores, were higher for patients who experienced lactate panics than for both controls and patients who did not panic.

References (12)

  • American Psychiatric Association

    DSM-III: Diagnostic and Statistical Manual of Mental Disorders

    (1980)
  • I.L. Appleby et al.

    Biochemical indices of lactate-induced panic: A preliminary report paper

  • J.A. Bonn et al.

    Lactate-induced anxiety: Therapeutic applications

    British Journal of Psychiatry

    (1971)
  • D.J. Dillon et al.

    Some physiological, biochemical and psychological concomitants of lactate-induced panic

  • D. Kelly et al.

    Anxiety and the effects of sodium lactate assessed clinically and physiologically

    British Journal of Psychiatry

    (1971)
  • M.R. Liebowitz et al.

    Lactate provocation of panic attacks: I. Clinical and behavioral findings

    Archives of General Psychiatry

    (1984)
There are more references available in the full text version of this article.

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Donald J. Dillon, Ph.D., is Associate Research Scientist (Psychology); Jack M. Gorman, M.D., Michael R. Liebowitz, M.D., and Abby J. Fyer, M.D., are Assistant Professors of Clinical Psychiatry; and Donald F. Klein, M.D., is Director of Research and Professor of Psychiatry, New York State Psychiatric Institute and the Department of Psychiatry, College of Physicians and Surgeons, Columbia University.

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