Elsevier

Molecular Brain Research

Volume 65, Issue 2, 5 March 1999, Pages 216-219
Molecular Brain Research

Short communication
Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development

https://doi.org/10.1016/S0169-328X(99)00022-4Get rights and content

Abstract

Recently, sortilin a non G-protein-coupled receptor has been identified as the 100-kDa neurotensin receptor. In this paper we describe the expression of its gene during mouse embryonal development. We show that the nervous system is the main location of sortilin gene expression and that with ongoing development the forebrain exhibits the highest accumulation of transcripts.

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Acknowledgements

We thank Drs. U. Borgmeyer and W. Hampe for helpful discussions and for critical reading of the manuscript, O. Sperl for help with the figures and K. Hilke-Steen for help in preparing the manuscript. A.N. was supported by the Danish Medical Research Council, the Carlsberg Foundation and the Lysgaard Foundation.

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