Notes & TipsDetermination of l-serine-O-phosphate in rat and mouse brain tissue using high-performance liquid chromatography and fluorimetric detection
Section snippets
Acknowledgments
The authors are grateful to Sara Tomlinson for preparation of the manuscript and to Jordyce van Muyden for assistance with figures. Funding was provided by the Canadian Institutes of Health Research and the Canada Research Chairs and Canada Foundation for Innovation programs.
References (8)
- et al.
Separation and quantification of d- and l-phosphoserine in rat brain using Nα-(2,4-dinitro-5-fluorophenyl)-d-alaninamide (Marfey’s reagent) by high-performance liquid chromatography with ultraviolet detection
J. Chromatogr. Biomed. Appl.
(1995) - et al.
Determination of d-serine and related neuroactive amino acids in human plasma by high-performance liquid chromatography with fluorimetric detection
J. Chromatogr. B
(2006) - et al.
l-Serine-O-phosphate in the central nervous system
Brain Res.
(2009) - et al.
Biochemistry and the Central Nervous System
(1971)
Cited by (5)
Selectivity and evolutionary divergence of metabotropic glutamate receptors for endogenous ligands and G proteins coupled to phospholipase C or TRP channels
2014, Journal of Biological ChemistryCitation Excerpt :We focused the analysis on the transmembrane region of the protein as defined by current mGluR1 structure PDBID 4OR2. Ten amino acids that are known to be present at substantial concentrations in cerebrospinal fluid (17) and d-SOP were applied to HEK 293 cells transfected with representative members for all subtypes of mGluR. mGluR1 naturally couples to Gαq so it was transfected alone but the other mGluR, which are Gαi/o coupled receptors, were co-transfected with a promiscuous G protein, either Gα15, or Gαqo.
Searching for an endogenous anti-alzheimer molecule: Identifying small molecules in the brain that slow alzheimer disease progression by inhibition of β-amyloid aggregation
2013, Journal of Psychiatry and NeuroscienceDetermination of amino acid neurotransmitters in mouse brain tissue using high-performance liquid chromatography with fluorescence detection
2013, Journal of Chinese Pharmaceutical SciencesModulation of glutamate release from parallel fibers by mGlu4 and pre-synaptic GABA <inf>A</inf> receptors
2012, Journal of Neurochemistry