Factors affecting smoking in schizophrenia
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Prevalence of tobacco smoking in people at clinical high-risk for psychosis: Systematic review and meta-analysis
2023, Schizophrenia ResearchAssociation between PLA2G6 gene polymorphism for calcium-independent phospholipase A2 and nicotine dependence among males with schizophrenia
2019, Prostaglandins Leukotrienes and Essential Fatty AcidsCigarette smoking and schizophrenia: a specific clinical and therapeutic profile? Results from the FACE-Schizophrenia cohort
2017, Progress in Neuro-Psychopharmacology and Biological PsychiatryCitation Excerpt :Studies examining the association of smoking status with positive or negative symptoms in patients with schizophrenia yielded inconsistent results. Sometimes an association is found ((Beratis et al., 2001; Fukui et al., 1995; Goff et al., 1992; Kao et al., 2011; Patkar et al., 2002; Ziedonis et al., 1994)) whereas not (Addington et al., 1997; Aguilar et al., 2005; Barnes et al., 2006; Dalack et al., 1999; Herrán et al., 2000; Hou et al., 2011; Levander et al., 2007; Zhang et al., 2011)). First generation antipsychotics (FGAs) remain commonly used in the treatment of schizophrenia with concurrent tobacco smoking, meanwhile an amount of evidence suggests that Second generation Antipsychotic (SGAs) may be more effective to treat both substance use disorder and psychotic disorder (Bédard et al., 2013; Samaha, 2014; El Hage et al., 2015).
Does tobacco use cause psychosis? Systematic review and meta-analysis
2015, The Lancet PsychiatryCitation Excerpt :If the study used terms such as “current smoker” or “smoker” without stipulating the number of cigarettes or packs smoked per day, we did not judge tobacco use to be daily and we did not include the study in the analysis of daily smokers. We defined onset of psychotic illness as either first psychiatric inpatient care,18–23 start of medical treatment,24 the first episode of psychosis,19,20,22,23,25–39 or the first diagnosis of psychotic illness.18,19,21,24,26–28,30,33,40–46 Because the definitions of age at onset differed, we had to assume that the difference in age at onset between smokers and non-smokers was similar, irrespective of the definition used.3
Assessment of cigarette smoking status with respect to symptomatic manifestation in first-episode schizophrenia patients
2015, Comprehensive PsychiatryCitation Excerpt :In addition, in the longitudinal study with a 26-year follow-up performed by Zammit et al. [40], cigarette smoking was found to serve as a protective factor with respect to the development of schizophrenia. It has been also proposed that schizophrenia patients may initiate smoking to alleviate neurophysiological and cognitive deficits that are present before the development of overt psychotic symptoms [41,42]. This assumption is corroborated by our findings of lower severity of negative and depression symptoms in FES patients with nicotine dependence.
Smoking topography and outcome expectancies among individuals with schizotypy
2013, Psychiatry ResearchCitation Excerpt :It is important to note that while smoking motives and smoking expectancies are similar constructs, motives refer to those reasons an individual endorses for why he/she continues to smoke (Fidler and West, 2009), whereas expectancies are the positive or negative consequences an individual expects to get from smoking (Copeland et al., 1995). As up to 86% of individuals with schizophrenia start smoking prior to illness onset (de Leon, 1996; Kelly and McCreadie, 1999; McEvoy and Brown, 1999; Beratis et al., 2001; de Leon et al., 2002a, 2002b; Riala et al., 2004), there is evidence that medication side effects and symptom severity are not to blame for increased smoking prevalence. This suggests a shared vulnerability between cigarette smoking and schizophrenia (e.g., de Leon and Diaz, 2005).