Abstract
Recently, sortilin a non G-protein-coupled receptor has been identified as the 100-kDa neurotensin receptor. In this paper we describe the expression of its gene during mouse embryonal development. We show that the nervous system is the main location of sortilin gene expression and that with ongoing development the forebrain exhibits the highest accumulation of transcripts.
Copyright 1999 Elsevier Science B.V.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adaptor Proteins, Vesicular Transport
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Age Factors
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Animals
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Brain Chemistry / genetics*
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Gene Expression Regulation, Developmental*
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In Situ Hybridization
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Membrane Glycoproteins / genetics*
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Mice
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Nerve Tissue Proteins / genetics*
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Prosencephalon / chemistry
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Prosencephalon / embryology
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RNA Probes
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RNA, Messenger / analysis
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Receptors, Neurotensin / genetics*
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Sulfur Radioisotopes
Substances
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Adaptor Proteins, Vesicular Transport
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Membrane Glycoproteins
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Nerve Tissue Proteins
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RNA Probes
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RNA, Messenger
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Receptors, Neurotensin
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Sulfur Radioisotopes
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sortilin