Four-year follow-up study of sertraline and fluvoxamine in long-term treatment of unipolar subjects with high recurrence rate

L Franchini; M Gasperini; R Zanardi; E Smeraldi

doi:10.1016/s0165-0327(99)00113-5

Four-year follow-up study of sertraline and fluvoxamine in long-term treatment of unipolar subjects with high recurrence rate

J Affect Disord. 2000 Jun;58(3):233-6. doi: 10.1016/s0165-0327(99)00113-5.

Authors

L Franchini¹, M Gasperini, R Zanardi, E Smeraldi

Affiliation

¹ Istituto Scientifico H. San Raffaele, Department of Neuropsychiatric Sciences, School of Medicine, University of Milan, Via Prinetti 29, 20127, Milan, Italy. centro.affettivi@hsr.it

PMID: 10802132
DOI: 10.1016/s0165-0327(99)00113-5

Abstract

We prolonged from 24 to 48 months a follow-up study of unipolar subjects with high recurrence rate treated with fluvoxamine (N=25) and sertraline (N=22). During the two-year additional period a significant risk of recurrences was observed during the third year of follow-up, without differences in the two long-term therapy groups. During the fourth year no patients showed new episodes of illness.

Publication types

Clinical Trial

MeSH terms

Adult
Antidepressive Agents / therapeutic use*
Antidepressive Agents, Second-Generation / therapeutic use*
Depressive Disorder / drug therapy*
Female
Fluvoxamine / therapeutic use*
Follow-Up Studies
Humans
Male
Middle Aged
Recurrence
Sertraline / therapeutic use*
Treatment Outcome

Substances

Antidepressive Agents
Antidepressive Agents, Second-Generation
Fluvoxamine
Sertraline