Weight gain among schizophrenic patients treated with clozapine

Am J Psychiatry. 1992 May;149(5):689-90. doi: 10.1176/ajp.149.5.689.

Abstract

A retrospective chart review was used to assess weight changes in 36 chronic schizophrenic inpatients who were treated with clozapine after being treated with standard neuroleptics. The average weight gain during 6 months of clozapine treatment was 16.9 lb; 75.0% of the patients gained at least 10 lb. The results confirm previous findings of clozapine-associated weight gain.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / pharmacology
  • Antipsychotic Agents / therapeutic use
  • Chronic Disease
  • Clozapine / adverse effects
  • Clozapine / pharmacology*
  • Clozapine / therapeutic use
  • Female
  • Hospitalization
  • Humans
  • Male
  • Psychiatric Status Rating Scales
  • Retrospective Studies
  • Schizophrenia / drug therapy*
  • Schizophrenic Psychology
  • Weight Gain / drug effects*

Substances

  • Antipsychotic Agents
  • Clozapine