Abstract
The rubber-hand illusion (RHI), an illusion in which tactile sensations are referred to a synthetic alien limb, is enhanced in schizophrenia patients. Somatosensory evoked responses of the illusion were compared between schizophrenia patients and normal control subjects. Schizophrenia patients had significant alterations in long latency evoked responses during the illusion. These findings support the hypothesis of alterations in associative higher-level neuronal activity in schizophrenia. The findings support previous results pointing to alterations in associative brain regions in schizophrenia.
MeSH terms
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Adult
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Attention / physiology*
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Brain Mapping
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Cerebral Cortex / physiopathology
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Delusions / diagnosis
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Delusions / physiopathology
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Delusions / psychology
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Electroencephalography*
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Evoked Potentials, Somatosensory / physiology*
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Female
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Hand / innervation*
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Humans
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Illusions / physiology*
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Male
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Nerve Net / physiopathology
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Neurons / physiology
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Perceptual Distortion / physiology
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Psychiatric Status Rating Scales
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Reaction Time / physiology
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Schizophrenia / diagnosis
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Schizophrenia / physiopathology*
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Schizophrenic Psychology*
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Sensory Thresholds / physiology
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Somatosensory Cortex / physiology
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Touch / physiology*