Supplementary motor area (SMA) volume is associated with psychotic aberrant motor behaviour of patients with schizophrenia

Katharina Stegmayer; Helge Horn; Andrea Federspiel; Nadja Razavi; Tobias Bracht; Karin Laimböck; Werner Strik; Thomas Dierks; Roland Wiest; Thomas J Müller; Sebastian Walther

doi:10.1016/j.pscychresns.2014.05.002

Supplementary motor area (SMA) volume is associated with psychotic aberrant motor behaviour of patients with schizophrenia

Psychiatry Res. 2014 Jul 30;223(1):49-51. doi: 10.1016/j.pscychresns.2014.05.002. Epub 2014 May 14.

Affiliations

¹ University Hospital of Psychiatry, Bolligenstrasse 111, 3060 Bern Switzerland, Switzerland. Electronic address: stegmayer@puk.unibe.ch.
² University Hospital of Psychiatry, Bolligenstrasse 111, 3060 Bern Switzerland, Switzerland.
³ Support Center of Advanced Neuroimaging (SCAN), University Institute of Diagnostic and Interventional Neuroradiology, Inselspital, University of Bern, 3010 Bern, Switzerland.

PMID: 24853647
DOI: 10.1016/j.pscychresns.2014.05.002

Abstract

We aimed to investigate whether aberrant motor behavior in schizophrenia was associated with structural alterations in the motor system. Whole brain voxel based morphometry of patients with different severity of motor symptoms identified altered gray matter volume in the supplementary motor area (SMA), a key region of the motor system.

Keywords: Dimension; Movement disorder; Rating scale.

MeSH terms

Adult
Brain Mapping
Female
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging / methods*
Male
Motor Activity / physiology*
Motor Cortex / pathology*
Motor Cortex / physiopathology
Motor Skills / physiology
Psychomotor Performance
Psychotic Disorders / diagnosis*
Psychotic Disorders / physiopathology
Psychotic Disorders / psychology
Schizophrenia / classification
Schizophrenia / diagnosis*
Schizophrenia / physiopathology
Severity of Illness Index